General Biology 2: Genetic Disorders

Subject: Biology 2

Topic: Genetic Disorders

Difficulty: Hard

Questions: 5

Passing Score: 70%

Question #1 1 point

A patient is diagnosed with a condition resulting from "Trisomy 21." How does this specific
chromosomal abnormality differ from a "monogenic" disorder like Cystic Fibrosis?

A: It involves an entire extra chromosome (47 total) rather than a single gene mutation.

B: It is caused by environmental factors like chemical exposure.

C: It only affects the respiratory system, while monogenic disorders affect the whole body.

D: It is inherited only when both parents are carriers of a recessive trait.

Question #2 1 point

Why is Spina Bifida categorized as a "complex" or multifactorial disorder rather than a simple
chromosomal one?

A: It is caused by a missing chromosome.

B: It results from a combination of genetic predispositions and environmental factors during pregnancy.

C: It is strictly an autoimmune disease that prevents insulin production.

D: It is caused by the inheritance of two faulty genes that produce thick mucus.

Question #3 1 point

In a clinical setting, a doctor observes a patient with thick, sticky mucus clogging the lungs
and interfering with digestion. If this is a monogenic disorder, what is the underlying cause?

A: An extra copy of chromosome 13.

B: Plaque buildup in the arteries (atherosclerosis).

C: Inheriting two faulty genes that affect organ secretions.

D: A transformation of normal cells into cancerous ones.

Question #4 1 point

A child is born with a genetic disorder, but neither parent expresses the disorder or carries the
trait in their family history. Which statement from the text explains this?

A: Genetic disorders are always inherited from both parents.

B: Some disorders happen only in the child through new mutations or code problems.

C: This is a result of selective breeding.

D: This can only happen if the child has Type 2 Diabetes.

Question #5 1 point

What is a primary distinction between the progression of Type 1 and Type 2 Diabetes?

A: Type 1 is an autoimmune issue preventing insulin production, while Type 2 involves the body's inability to use insulin properly

B: Type 1 is caused by diet, while Type 2 is strictly chromosomal.

C: Type 1 only occurs during pregnancy, while Type 2 is lifelong.

D: There is no difference; both are single-gene monogenic disorders.

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